The information about medications is for informational purposes only. We are not responsible for any potential negative consequences of their use.
MESTION (KALIMIN) 60 mg (ITALY)
9у.е. (На замовлення)
Dosage form: tablets.
Pharmacotherapeutic group: drugs affecting the central nervous system.
Clinical characteristics
Indications:
• Myasthenia gravis;
• Myasthenic syndrome (Lambert-Eaton myasthenic syndrome) as part of combination therapy with guanidine.
Contraindications:
The drug is contraindicated in:
• hypersensitivity to the components;
• mechanical obstruction of the gastrointestinal tract or urinary tract;
• bronchial asthma, spastic bronchitis, iritis, breastfeeding.
Method of administration and dosage:
Dosage and duration of treatment are determined individually by the physician.
Myasthenia gravis:
1–3 tablets 3–4 times a day (180–720 mg per day).
Myasthenic syndrome:
Initial dose — 180–720 mg per day in 3–4 doses. If necessary, guanidine is added at a dose of 375–1000 mg.
For patients with kidney diseases:
Reduction of dosage or increase in intervals between doses.
Side effects:
• Nausea, vomiting, diarrhea, abdominal pain;
• Bradycardia, hypotension;
• Increased salivation, bronchospasm;
• Increased sweating, skin rashes.
Overdose:
May cause cholinergic crisis. Treatment: discontinuation of the drug, gastric lavage, administration of atropine sulfate.
Use during pregnancy and breastfeeding:
Prescribed only after risk assessment. The drug is excreted in breast milk, so breastfeeding should be discontinued.
Children:
Not used for the treatment of children.
Precautions:
Use with caution in cases of peptic ulcer, heart diseases, bradycardia, diabetes mellitus.
Interaction with other drugs:
Enhances the action of parasympathomimetics and anticholinesterase drugs. May reduce the effect of corticosteroids and some antibiotics.
Pharmacological properties:
• Pharmacodynamics: inhibits cholinesterase, enhances the action of acetylcholine.
• Pharmacokinetics: maximum concentration is reached in 1.7–3.2 hours. Excreted mainly by the kidneys.
Pharmaceutical characteristics:
White tablets, biconvex, elongated with a score line.
Shelf life: 3 years. After opening the bottle — 6 months.
Storage conditions:
Store at a temperature not exceeding 30°C in a place inaccessible to children.
Pack contains 20 tablets.
Pharmacotherapeutic group: drugs affecting the central nervous system.
Clinical characteristics
Indications:
• Myasthenia gravis;
• Myasthenic syndrome (Lambert-Eaton myasthenic syndrome) as part of combination therapy with guanidine.
Contraindications:
The drug is contraindicated in:
• hypersensitivity to the components;
• mechanical obstruction of the gastrointestinal tract or urinary tract;
• bronchial asthma, spastic bronchitis, iritis, breastfeeding.
Method of administration and dosage:
Dosage and duration of treatment are determined individually by the physician.
Myasthenia gravis:
1–3 tablets 3–4 times a day (180–720 mg per day).
Myasthenic syndrome:
Initial dose — 180–720 mg per day in 3–4 doses. If necessary, guanidine is added at a dose of 375–1000 mg.
For patients with kidney diseases:
Reduction of dosage or increase in intervals between doses.
Side effects:
• Nausea, vomiting, diarrhea, abdominal pain;
• Bradycardia, hypotension;
• Increased salivation, bronchospasm;
• Increased sweating, skin rashes.
Overdose:
May cause cholinergic crisis. Treatment: discontinuation of the drug, gastric lavage, administration of atropine sulfate.
Use during pregnancy and breastfeeding:
Prescribed only after risk assessment. The drug is excreted in breast milk, so breastfeeding should be discontinued.
Children:
Not used for the treatment of children.
Precautions:
Use with caution in cases of peptic ulcer, heart diseases, bradycardia, diabetes mellitus.
Interaction with other drugs:
Enhances the action of parasympathomimetics and anticholinesterase drugs. May reduce the effect of corticosteroids and some antibiotics.
Pharmacological properties:
• Pharmacodynamics: inhibits cholinesterase, enhances the action of acetylcholine.
• Pharmacokinetics: maximum concentration is reached in 1.7–3.2 hours. Excreted mainly by the kidneys.
Pharmaceutical characteristics:
White tablets, biconvex, elongated with a score line.
Shelf life: 3 years. After opening the bottle — 6 months.
Storage conditions:
Store at a temperature not exceeding 30°C in a place inaccessible to children.
Pack contains 20 tablets.
