Plasmapheresis (blood purification to remove toxic substances)

Plasmapheresis – is a method of extracorporeal (outside the body) therapy, the essence of which is in the removal of plasma, which contains toxic and metabolic substances, carriers of disease causes.

Depending on the plasma obtaining method, there are machine-based, centrifugal, membrane, and sedimentation (settling) plasmapheresis. In the modern version, plasmapheresis is conducted in special plasma filters or separators, where blood is separated into formed elements (cells) and plasma. The plasma is removed, and blood cells along with plasma-replacing solutions are returned to the patient's bloodstream. To perform the procedure, the patient is connected to the device through one of the peripheral veins, using a catheter, connected to a set of tubes and a plasma filter. The entire process of plasma extraction and return of cells is performed automatically and safely, as only sterile sets of disposable materials are used. The duration of the procedure is 1.5-2 hours. Plasmapheresis is conducted to reduce the concentration of harmful proteins, lipids, hormones, toxins, antigens, antibodies, and immune complexes in the plasma. Unfortunately, the method is not selective and does not allow removal of specifically those components that cause or sustain the disease. Therefore, along with plasma, many other substances are removed from the body, some of which are necessary for the body to maintain normal metabolism. Therefore, The method under certain conditions requires replacement therapy with proteins and other drugs. Currently, plasmapheresis is not only of technological importance as a method of preparation for selective (immunosorption) or semi-selective (cryoapheresis) removal of harmful substances from the blood, but is also used as an independent method of detoxification. Indications for performing plasmapheresis, which in the 20th century were excessively broad (over 200 diseases), have gradually narrowed in recent years. International multicenter studies have shown that the unconditional effect of plasmapheresis is limited to the following diseases and syndromes: Indications

heart lesions in allergic and autoimmune diseases
viral damage to the heart muscle (viral myocarditis)
complications of myocardial infarction
heart inflammation of autoimmune origin
atherosclerosis
systemic vasculitis
bronchial asthma
fibrosing alveolitis
hemosiderosis

non-specific ulcerative colitis

Crohn's disease

chronic autoimmune liver inflammation;

toxic encephalopathies

diabetes and its complications (damage to the vessels of the eyes, kidneys, brain, legs)

reduced sensitivity to insulin; Addison's disease

psoriasis joint damage in psoriasis

pemphigus

herpes

severe allergic conditions

toxicoderma.

atopic dermatitis

rheumatoid arthritis

systemic lupus erythematosus

dermatomyositis

- Systemic sclerosis - Pollinosis - Allergic reactions to various substances - Allergic reactions to physical factors: sunlight, heat, cold, etc. - Eye damage in diseases of internal secretion organs - Chronic inflammation of the vascular tunic of the eye, chronic inflammation of the orbit - Damage to the blood vessels of the eyeball in diabetes - Glomerulonephritis, inflammation of the kidneys in systemic lupus erythematosus - Goodpasture syndrome - Severe infections of the kidneys and ureters

severe kidney function impairment

multiple sclerosis

chronic infectious diseases of the nervous system

allergic inflammation of brain tissue

ethyl alcohol poisoning, hangover syndrome

drug addiction, toxicomania

Contraindications Absolute contraindications for performing plasmapheresis (contraindications, under which the procedure should not be performed under any circumstances):